Switching to nevirapine (NVP) significantly increases high-density lipoprotein cholesterol (HDL-C) in treatment-experienced patients (NEVICOR study)
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منابع مشابه
Switching to nevirapine (NVP) significantly increases high-density lipoprotein cholesterol (HDL-C) in treatment-experienced patients (NEVICOR study)
Results Among 130 pts included in the study, 119 (91%) could be evaluated. BL characteristics: median age 44, female 24%, current smokers 53%. Previous AIDS 29%, CD4 count 502/mm. Time on ARV therapy 42 months. Previous therapy: efavirenz 38%, 3 NRTI 12%, PI 50%. Accompanying nucleosides were tenofovir/emtricitabine in 69%, and abacavir/lamivudine in 31%. Table 1 shows the 24-week results of li...
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متن کاملNevirapine increases high-density lipoprotein cholesterol concentration by stimulation of apolipoprotein A-I production.
OBJECTIVE The purpose of this study was to investigate the mechanism by which the nonnucleoside reverse transcriptase inhibitor (NNRTI) nevirapine (NVP) increases high-density lipoprotein cholesterol (HDLc) in treatment-experienced human immunodeficiency virus-1 (HIV-1)-infected patients. METHODS AND RESULTS Twelve HIV-1 infected patients, with stably suppressed HIV-1 viral load using AZT/3TC...
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ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2010
ISSN: 1758-2652,1758-2652
DOI: 10.1186/1758-2652-13-s4-p79